Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 14/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483363 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BP2RX7OPRK1 | |
| SCHEMBL9483220 | 0.83 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL9484405 | 0.82 | ITGB3 (0.55) | ITGB3ITGA2BP2RX7 | |
| SCHEMBL9819722 | 0.80 | ITGB3 (0.52) | ITGB3ITGA2BOPRK1 | |
| SCHEMBL8750802 | 0.80 | TACR1 (0.60) | ITGB3ITGA2BP2RX7OPRK1 | |
| SCHEMBL8750811 | 0.80 | TACR1 (0.60) | ITGB3ITGA2BP2RX7OPRK1 | |
| SCHEMBL11257249 | 0.78 | TACR1 (0.63) | P2RX7 | |
| SCHEMBL11257246 | 0.78 | TACR1 (0.63) | P2RX7 | |
| SCHEMBL11232416 | 0.77 | ITGB3 (0.62) | ITGB3ITGA2BP2RX7 | |
| SCHEMBL9634993 | 0.73 | P2RX7 (0.69) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |