Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.59 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.59 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 7/20 | 0.49 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | FNTA | P49354 | 1/20 | 0.48 |
| ▸ | FNTB | P49356 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9483544 | 0.90 | ITGB3 (0.59) | ITGB3ITGA2BP2RX7OPRK1 | |
| SCHEMBL9819722 | 0.85 | ITGB3 (0.52) | ITGB3ITGA2BOPRK1CHRM3PRSS1 | |
| SCHEMBL8750802 | 0.84 | TACR1 (0.60) | ITGB3ITGA2BP2RX7CTSLCTSB | |
| SCHEMBL8750811 | 0.84 | TACR1 (0.60) | ITGB3ITGA2BP2RX7CTSLCTSB | |
| SCHEMBL11257249 | 0.82 | TACR1 (0.63) | P2RX7CTSLCTSBCTSK | |
| SCHEMBL11257246 | 0.82 | TACR1 (0.63) | P2RX7CTSLCTSBCTSK | |
| SCHEMBL9634993 | 0.81 | P2RX7 (0.69) | MC4RP2RX7 | |
| SCHEMBL9484550 | 0.81 | OPRK1 (0.67) | OPRK1CHRM3 | |
| SCHEMBL9484534 | 0.81 | OPRK1 (0.67) | OPRK1CHRM3 | |
| SCHEMBL9483704 | 0.81 | MC4R (0.61) | MC4RP2RX7CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5245034-A | Compound having vessel smooth muscle relaxation activity | Hidaka, Kiroyoshi (JP) | 1993-09-14 | — | — | US | disclosed |
| US-5216150-A | Muscle relaxant; enzyme inhibitor and platelet aggutination inhibitor | Hidaka, Hiroyoshi (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5081246-A | Isoquinolino sulfonamino derivatives | Hidaka, Hiroyoshi (JP) | 1992-01-14 | — | — | US | disclosed |