Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9487573 | 0.83 | TAOK1 (0.53) | HRH3SCN3ACD274NPC1RAB9A | |
| SCHEMBL9490780 | 0.83 | CYSLTR1 (0.50) | ALOX5AP | |
| SCHEMBL9492340 | 0.80 | GAA (0.48) | SCN3ACD274KDM4EALDH1A1GAA | |
| SCHEMBL9490891 | 0.77 | ALDH1A1 (0.50) | SCN3AALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9490621 | 0.77 | MAOB (0.52) | SCN3AALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL9491558 | 0.77 | PARP10 (0.46) | HRH3SCN3APARP10 | |
| SCHEMBL17712567 | 0.76 | NPC1 (0.55) | HRH3ALOX5APPARP10KDM4EALDH1A1 | |
| SCHEMBL9488808 | 0.76 | LIPG (0.57) | HRH3SCN3AMAPT | |
| SCHEMBL9489556 | 0.75 | TAOK1 (0.48) | HRH3SCN3ACD274ALDH1A1TAS1R3 | |
| SCHEMBL19366283 | 0.75 | HRH3 (0.51) | HRH3ALOX5APPARP10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |