Erbulozole

Erbulozole

SCHEMBL9488166

CCOC(=O)Nc1ccc(SCC2COC(Cn3ccnc3)(c3ccc(OC)cc3)O2)cc1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.40
CYP19A1 P11511 5/20 0.40
CYP17A1 P05093 4/20 0.40
CYP11B1 P15538 3/20 0.40
CYP51A1 Q16850 2/20 0.40
CYP21A2 P08686 3/20 0.40
USP2 O75604 2/20 0.40
MAPT P10636 2/20 0.40
MAPK1 P28482 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
SLC22A1 O15245 1/20 0.40
ABCC4 O15439 1/20 0.40
CYP27B1 O15528 1/20 0.40
CYP26A1 O43174 1/20 0.40
NR1I2 O75469 1/20 0.40
GMNN O75496 1/20 0.40
ABCB11 O95342 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Erbulozole SCHEMBL3824 1.00 CYP3A4 (0.40) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
Erbulozole SCHEMBL9488172 1.00 CYP3A4 (0.40) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
Erbulozole SCHEMBL27849451 0.99 CYP3A4 (0.40) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9488205 0.92 CYP3A4 (0.42) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9488211 0.92 CYP3A4 (0.42) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9490358 0.92 CYP3A4 (0.42) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9489826 0.92 CYP3A4 (0.42) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9488791 0.92 TBXAS1 (0.43) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9490323 0.92 CYP3A4 (0.39) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1
SCHEMBL9488796 0.92 TBXAS1 (0.43) CYP3A4CYP19A1CYP17A1CYP11B1CYP51A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026505-A2 DISRUPTION OF TELOCYTE ACTIVITY PATEL AMIT (US) 2024-02-01 WO claimed
EP-3441089-B1 TREATMENT METHODS USING ADENOVIRUS VASCULAR BIOGENICS LTD (IL) 2022-12-14 EP claimed
US-5236944-A C1-4 alkyl(4-(2-(4-C1-4-alkylphenyl)-2(1H-imidazol-1-ylmethyl) -1,3-dioxolan-4-ylemthlthio)phenyl)carbamate JANSSEN PHARMACEUTICA N.V. (BE) 1993-08-17 US claimed
EP-4748838-A1 BROAD SPECTRUM ANTI-CANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-27 EP disclosed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CITY OF HOPE (US) 2026-05-26 US disclosed
US-12630527-B2 Broad spectrum anti-cancer compounds THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-19 US disclosed
CN-122010947-A Antagonists of adenosine A2a receptors 阿道尔克斯治疗有限公司 2026-05-12 CN disclosed
US-12622910-B2 Inhibitors of Bruton's tyrosine kinase and methods of their use JANSSEN PHARMACEUTICA NV (BE) 2026-05-12 US disclosed
US-12617796-B2 Antagonists of the adenosine A2a receptor JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 US disclosed
US-12617845-B2 SMC1A antibodies and uses thereof CITY OF HOPE (US) 2026-05-05 US disclosed
US-11254651-B2 Histone methyltransferase inhibitors GLOBAL BLOOD THERAPEUTICS, INC. (US) 2022-02-22 US disclosed
US-20220048863-A1 DNA2 INHIBITORS FOR CANCER TREATMENT CALIFORNIA INSTITUTE OF TECHNOLOGY 2022-02-17 US disclosed
EP-3953372-A2 CHIMERIC ANTIGEN RECEPTOR MODIFIED T-CELLS (CAR-T) FOR THE TREATMENT OF HEMATOLOGICAL AND SOLID TUMOR CANCERS The Regents of The University of California (US) 2022-02-16 EP disclosed
CN-114040915-A Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors 里伯赛恩斯有限责任公司 2022-02-11 CN disclosed
WO-2022031952-A2 TREATMENTS FOR CANCERS HAVING KRAS MUTATIONS CITY OF HOPE (US) 2022-02-10 WO disclosed
CN-114025844-A Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2022-02-08 CN disclosed
WO-2022023772-A1 ANTAGONIST COMPOUNDS AdoRx Therapeutics Limited (GB) 2022-02-03 WO disclosed
CN-215643385-U Device for direct drug infusion 基因泰克股份有限公司 2022-01-25 CN disclosed
US-5236944-A C1-4 alkyl(4-(2-(4-C1-4-alkylphenyl)-2(1H-imidazol-1-ylmethyl) -1,3-dioxolan-4-ylemthlthio)phenyl)carbamate JANSSEN PHARMACEUTICA N.V. (BE) 1993-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12622910-B2 Inhibitors of Bruton's tyrosine kinase and methods of their use BCL6B, BCL9, BTK CYP3A4 3235/4885CYP19A1 3807/4885CYP17A1 2671/4885
US-12637510-B2 Oncolytic virus compositions and methods for the treatment of cancer CD47, IGLV6-57, STING1 CYP3A4 4802/4885CYP19A1 3753/4885CYP17A1 4407/4885
US-12617796-B2 Antagonists of the adenosine A2a receptor ADORA2A, ADORA2B, ADORA3 CYP3A4 2439/4885CYP19A1 3299/4885CYP17A1 4549/4885
US-12617845-B2 SMC1A antibodies and uses thereof SMC1A, SMCHD1, SMC2 CYP3A4 3869/4885CYP19A1 2410/4885CYP17A1 1547/4885
US-12630527-B2 Broad spectrum anti-cancer compounds YTHDF3, YTHDF1, YTHDF2 CYP3A4 4735/4885CYP19A1 3711/4885CYP17A1 4019/4885
US-11254651-B2 Histone methyltransferase inhibitors EHMT1, EHMT2, BMI1 CYP3A4 4515/4885CYP19A1 4137/4885CYP17A1 4442/4885
US-20220048863-A1 DNA2 INHIBITORS FOR CANCER TREATMENT DNA2, TOP2A, TOP2B CYP3A4 4433/4885CYP19A1 3983/4885CYP17A1 4062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.