Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.35 |
| ▸ | ABAT | P80404 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499679 | 0.81 | — | — | |
| SCHEMBL5050902 | 0.76 | PARP10 (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL1663469 | 0.76 | PARP10 (0.65) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL9496291 | 0.75 | HSPB1 (0.39) | ALDH1A1KDM4ELMNAL3MBTL1KMT2A | |
| SCHEMBL9498019 | 0.74 | TEAD4 (0.45) | ALDH1A1LMNASMN1; SMN2POLBKMT2A | |
| SCHEMBL9496376 | 0.74 | CA1 (0.48) | ALDH1A1KDM4EPARP10L3MBTL1KMT2A | |
| SCHEMBL9497883 | 0.74 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2PARP10POLBKMT2A | |
| SCHEMBL9500512 | 0.74 | MAOA (0.45) | ALDH1A1KDM4ELMNASMN1; SMN2CYP2A6 | |
| SCHEMBL9498280 | 0.74 | MAPT (0.45) | ALDH1A1LMNACYP2A6KMT2AMAPT | |
| SCHEMBL9364922 | 0.73 | LTA4H (0.50) | KDM4EPARP10KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343441-B1 | FLUORINATED BIS-ARYLOXY-SUBSTITUTED ALKENES, METHOD FOR THEIR PRODUCTION AN THEIR APPLICATION | BAYER AG (DE) | 1993-03-24 | — | — | EP | disclosed |
| US-4990633-A | Used as insulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| EP-0343441-A2 | Fluorinated bis-aryloxy-substituted alkenes, method for their production an their application | BAYER AG (DE) | 1989-11-29 | — | — | EP | disclosed |