SCHEMBL9500519

SCHEMBL9500519

OC(c1ccc(Oc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)cc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NR1H2 P55055 14/20 0.54
▸ NR1H3 Q13133 14/20 0.54
▸ MLYCD O95822 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131990 0.84 NR1H2 (0.68) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL7131226 0.82 MLYCD (0.56) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL24901417 0.82 NR1H2 (0.50) NR1H2NR1H3MLYCDSMN1; SMN2
Water SCHEMBL1684070 0.82 NR1H2 (0.65) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL9621271 0.77 NR1H2 (0.60) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL24901413 0.77 NR1H2 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL13374679 0.77 NR1H2 (0.51) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL28365026 0.76 KIF11 (0.64) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL1516045 0.75 ESR1 (0.61) NR1H2NR1H3MLYCDSMN1; SMN2
SCHEMBL8021367 0.75 NR1H2 (0.58) NR1H2NR1H3MLYCDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250368595-A1 NOVEL MOLECULES Xeniopro GmbH (DE) 2025-12-04 — — US claimed
US-20250368595-A1 NOVEL MOLECULES Xeniopro GmbH (DE) 2025-12-04 — — US disclosed
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2023-05-11 — — US disclosed
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY Xeniopro GmbH (DE) 2022-08-11 — — US disclosed
US-10363740-B2 Liquid ejection head and method for manufacturing the same CANON KABUSHIKI KAISHA (JP) 2019-07-30 — — US disclosed
US-20180201018-A1 LIQUID EJECTION HEAD AND METHOD FOR MANUFACTURING THE SAME CANON KABUSHIKI KAISHA (JP) 2018-07-19 — — US disclosed
US-20180201018-A1 LIQUID EJECTION HEAD AND METHOD FOR MANUFACTURING THE SAME CANON KABUSHIKI KAISHA (JP) 2018-07-19 — — US disclosed
EP-1766473-B1 CATIONIC PHOTOPOLYMERIZABLE EPOXY RESIN COMPOSITION, MINUTE STRUCTURAL MEMBER USING THE SAME AND METHOD FOR MANUFACTURING MINUTE STRUCTURAL MEMBER CANON KK (JP) 2015-09-09 — — EP disclosed
US-7575851-B2 Cationic photopolymerizable epoxy resin composition, minute structural member using the same and method for manufacturing minute structural member CANON KABUSHIKI KAISHA (JP) 2009-08-18 — — US disclosed
US-7553544-B2 Precursor composition for optical resin, resin for optical use, optical element, and optical article NIKON CORPORATION (JP) 2009-06-30 — — US disclosed
US-7553544-B2 Precursor composition for optical resin, resin for optical use, optical element, and optical article NIKON CORPORATION (JP) 2009-06-30 — — US disclosed
US-20080008971-A1 Cationic Photopolymerizable Epoxy Resin Composition, Minute Structural Member Using the Same and Method for Manufacturing Minute Structural Member CANON KABUSHIKI KAISHA (JP) 2008-01-10 — — US disclosed
EP-0317883-B1 PARTIALLY FLUORINATED DIPHENYL ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1993-06-16 — — EP disclosed
US-4992593-A Partially fluorinated diphenyl ethers, processes for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220249500-A1 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR NR1H2 1555/4885NR1H3 1622/4885MLYCD 2363/4885
US-20250368595-A1 NOVEL MOLECULES MUSK, IKZF3, TYR NR1H2 2979/4885NR1H3 3140/4885MLYCD 2073/4885
US-20230141913-A2 PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY AHR, MUSK, TYR NR1H2 1555/4885NR1H3 1622/4885MLYCD 2363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback