Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.52 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.52 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7230519 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL27866193 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7230019 | 0.81 | KDM4E (0.44) | NR3C2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL950143 | 0.81 | PTGS1 (0.64) | NR3C2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6763705 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7239926 | 0.81 | MAPT (0.46) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL17064914 | 0.81 | PTGS1 (0.64) | NR3C2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12528203 | 0.80 | KDM4E (0.66) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL8689010 | 0.80 | PTGS2 (0.47) | KDM4EALDH1A1HPGDHSD17B10TSHR | |
| SCHEMBL7237134 | 0.80 | KDM4E (0.42) | NR3C2KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121621-B1 | LXR AND FXR MODULATORS | EXELIXIS PATENT CO LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| EP-2121621-B1 | LXR AND FXR MODULATORS | EXELIXIS PATENT CO LLC (US) | 2014-05-07 | — | — | EP | disclosed |
| US-7998995-B2 | LXR and FXR modulators | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |
| US-7998995-B2 | LXR and FXR modulators | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |
| US-7998995-B2 | LXR and FXR modulators | EXELIXIS PATENT COMPANY LLC (US) | 2011-08-16 | — | — | US | disclosed |
| US-7968573-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-06-28 | — | — | US | disclosed |
| EP-1937664-B1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-7867949-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-11 | — | — | US | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
| CN-1298706-C | Insecticidal diamides | DU PONT (US) | 2007-02-07 | — | — | CN | disclosed |
| US-7148217-B2 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| US-20060258649-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | SELBY THOMAS P | 2006-11-16 | — | — | US | disclosed |
| CN-1568144-A | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | DU PONT (US) | 2005-01-19 | — | — | CN | disclosed |
| CN-1555364-A | Insecticidal diamides | �Ű˾ | 2004-12-15 | — | — | CN | disclosed |
| US-20040214828-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-10-28 | — | — | US | disclosed |
| US-20040063738-A1 | Substituted heterocyclic phthalic acid diamide arthropodicides | E.I. DU PONT DE NEMOURS AND COMPANY | 2004-04-01 | — | — | US | disclosed |
| EP-1341780-A2 | SUBSTITUTED HETEROCYCLIC PHTHALIC ACID DIAMIDE ARTHROPODICIDES | E. I. du Pont de Nemours and Company (US) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048137-A2 | SUBSTITUTED HETEROCYCLIC PHTHALIC ACID DIAMIDE ARTHROPODICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214828-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | NR0B1, IPO5, RER1 | RXRA 1529/4885NR1H2 748/4885NR1H3 2085/4885 |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, H1-2, H1-0 | RXRA 1418/4885NR1H2 2869/4885NR1H3 3657/4885 |
| US-20040063738-A1 | Substituted heterocyclic phthalic acid diamide arthropodicides | DDT, QDPR, DDX6 | RXRA 1630/4885NR1H2 4270/4885NR1H3 4602/4885 |
| US-20060258649-A1 | Iminobenzoxazines, iminobenzthiazines and iminoquinazolines for controlling invertebrate pests | NR0B1, NR1I2, NR0B2 | RXRA 653/4885NR1H2 12/4885NR1H3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.