Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509549 | 0.81 | KMT2A (0.43) | MEN1KMT2AHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL9509591 | 0.73 | FFAR1 (0.39) | L3MBTL1GAA | |
| SCHEMBL9510856 | 0.73 | RAB9A (0.44) | CTSBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL31172708 | 0.72 | RAB9A (0.46) | CTSBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL6158106 | 0.72 | SMN1; SMN2 (0.48) | RAB9AMEN1KMT2ANPC1HPGD | |
| SCHEMBL9507496 | 0.71 | HTR7 (0.46) | CTSBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9510871 | 0.70 | ALDH1A1 (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL31172667 | 0.70 | TP53 (0.48) | CTSBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL31172632 | 0.68 | RAB9A (0.44) | CTSBRAB9AMEN1KMT2ANPC1 | |
| SCHEMBL9507226 | 0.67 | L3MBTL1 (0.43) | MEN1KMT2AHPGDHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0358305-B1 | MERCAPTO-PHENYLALCANOYLAMINO ACID AMIDES, THEIR PREPARATION AND THEIR USE AS COLLAGENASE INHIBITORS | BEECHAM GROUP PLC (GB) | 1993-08-25 | — | — | EP | disclosed |
| US-5124322-A | Antiarthritic agents | BEECHAM GROUP P.L.C. (GB) | 1992-06-23 | — | — | US | disclosed |
| EP-0358305-A1 | Mercapto-phenylalcanoylamino acid amides, their preparation and their use as collagenase inhibitors | BEECHAM GROUP PLC (GB) | 1990-03-14 | — | — | EP | disclosed |