Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284428 | 0.90 | PGK1 (0.40) | ESR1ESR2KIF11TSHRALDH1A1 | |
| SCHEMBL9621272 | 0.83 | KIF11 (0.46) | ESR1ESR2KIF11CA1CA2 | |
| SCHEMBL1026404 | 0.82 | ESR1 (0.64) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL2868121 | 0.82 | ESR1 (0.62) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL8560690 | 0.81 | USP2 (0.43) | ESR1ESR2CYP3A4RAB9APGK1 | |
| SCHEMBL1357633 | 0.80 | ALDH1A1 (0.50) | KIF11LMNATSHRALDH1A1CA1 | |
| SCHEMBL15084263 | 0.80 | ESR1 (0.54) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL2776477 | 0.79 | MLYCD (0.50) | CYP3A4LMNATSHRMEN1CA1 | |
| SCHEMBL4982243 | 0.79 | KIF11 (0.46) | ESR1ESR2KIF11CYP3A4LMNA | |
| SCHEMBL5068336 | 0.78 | ESR1 (0.58) | ESR1ESR2KIF11CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965021-A | Preparation method of 2-(4- hydroxy phenyl) hexafluoroisopropanol | UNIV NANJING INF SCI & TECH | 2014-08-06 | — | — | CN | claimed |
| CN-103965021-B | A kind of preparation method of 2-(4-hydroxy phenyl) hexafluoroisopropanol | NANJING UNIVERSITY OF INFORMATION SCIENCE AND TECHNOLOGY (CN) | 2015-11-18 | — | — | CN | disclosed |
| CN-103965021-A | Preparation method of 2-(4- hydroxy phenyl) hexafluoroisopropanol | UNIV NANJING INF SCI & TECH | 2014-08-06 | — | — | CN | disclosed |
| EP-0286991-B1 | PROCESS FOR PREPARING FLUORINE-SUBSTITUTED ALICYCLIC DIOLS | DAIKIN INDUSTRIES, LIMITED (JP) | 1993-08-18 | — | — | EP | disclosed |