Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1284428 | 0.88 | PGK1 (0.40) | KIF11ALDH1A1NR1H2NR1H3PGK1 | |
| SCHEMBL9621272 | 0.81 | KIF11 (0.46) | KIF11NR1H2NR1H3PGK1PGK2 | |
| SCHEMBL445852 | 0.80 | KIF11 (0.54) | KIF11PTGS1ALDH1A1KDM4ETDP1 | |
| SCHEMBL8733113 | 0.80 | KIF11 (0.59) | KIF11PTGS1ALDH1A1KDM4ETDP1 | |
| SCHEMBL8560690 | 0.79 | USP2 (0.43) | CYP3A4NR1H2NR1H3RAB9APGK1 | |
| SCHEMBL9508396 | 0.79 | ESR1 (0.56) | KIF11PTGS1ALDH1A1KDM4EMAPT | |
| SCHEMBL1357633 | 0.78 | ALDH1A1 (0.50) | KIF11ALDH1A1MAPTALOX15NR1H2 | |
| SCHEMBL2776477 | 0.77 | MLYCD (0.50) | TDP1MEN1KMT2ACYP3A4NR1H2 | |
| SCHEMBL4609826 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4ETDP1MAPTMEN1 | |
| SCHEMBL289673 | 0.76 | NR1H2 (0.56) | KIF11GCKNR1H2NR1H3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102053108-B | Method for preparing hexafluorobisphenol A modified carbon nanotube gas-sensitive sensing material | UNIV SHANGHAI JIAOTONG | 2012-09-19 | — | — | CN | disclosed |
| CN-102053108-A | Method for preparing hexafluorobisphenol A modified carbon nanotube gas-sensitive sensing material | UNIV SHANGHAI JIAOTONG | 2011-05-11 | — | — | CN | disclosed |
| US-7385063-B2 | Method for preparing imidazole derivatives | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-06-10 | — | — | US | disclosed |
| EP-1353662-B1 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-20040087627-A1 | Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-05-06 | — | — | US | disclosed |
| EP-1353662-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-10-22 | — | — | EP | disclosed |
| WO-2002058690-A2 | METHODS FOR THE TREATMENT OF DISEASES USING MALONYL-COA DECARBOX YLASE INHIBITORS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-08-01 | — | — | WO | disclosed |
| US-4230635-A | ANTIHYPERTENSIVE, HERBICIDES, FUNGICIDES | SCHERING CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4093742-A | Anti-hypertensive polyhaloisopropyl-substituted arylureas | SCHERING CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-3931210-A | Production of p-aminobenzoic acid | AKZO N.V. (NL) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087627-A1 | Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors | ME2, PC, ACACA | KIF11 3330/4885PTGS1 1185/4885ALDH1A1 218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.