Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676910 | 0.75 | FAAH (0.30) | — | |
| SCHEMBL16628135 | 0.74 | DHFR (0.46) | SCN9AP2RX7MEN1KMT2ACYP11B1 | |
| SCHEMBL1283337 | 0.71 | SCN9A (0.39) | SCN9AMEN1KMT2ASCN5ADHFR | |
| SCHEMBL2745554 | 0.70 | ALDH1A1 (0.32) | MEN1KMT2AEPHX2 | |
| SCHEMBL4443853 | 0.69 | P2RX7 (0.46) | P2RX7CYP11B1CYP11B2EPHX2 | |
| SCHEMBL1634159 | 0.69 | KDM4E (0.54) | P2RX7MEN1KMT2A | |
| SCHEMBL6238419 | 0.68 | JAK2 (0.33) | — | |
| SCHEMBL2746865 | 0.68 | KDM4E (0.32) | MEN1KMT2A | |
| SCHEMBL28930432 | 0.68 | SCN9A (0.40) | SCN9ASCN5A | |
| SCHEMBL27923627 | 0.68 | KCNA3 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409740-B1 | Compound labelled with tritium, its preparation and use, especially in locating retinoid nuclear receptors | CIRD GALDERMA (FR) | 1993-11-03 | — | — | EP | claimed |
| EP-0409740-B1 | Compound labelled with tritium, its preparation and use, especially in locating retinoid nuclear receptors | CIRD GALDERMA (FR) | 1993-11-03 | — | — | EP | disclosed |
| EP-0409740-A1 | Compound labelled with tritium, its preparation and use, especially in locating retinoid nuclear receptors | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA, ( CIRD GALDERMA) (FR) | 1991-01-23 | — | — | EP | disclosed |