Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | ESRRG | P62508 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PGK1 | P00558 | 1/20 | 0.40 |
| ▸ | PGK2 | P07205 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5189401 | 0.82 | TSHR (0.57) | NR3C1CYP2C19KDM4EPTPN1CNR2 | |
| SCHEMBL10906279 | 0.78 | NR3C1 (0.49) | NR3C1CYP2C19PTPN1HPGDCNR2 | |
| SCHEMBL28565303 | 0.78 | CYP2C19 (0.71) | NR3C1CYP2C19CNR2TSHR | |
| SCHEMBL264790 | 0.78 | PTPN1 (0.52) | NR3C1CYP2C19PTPN1CNR2TSHR | |
| SCHEMBL9512466 | 0.75 | ENPP2 (0.42) | PGK1PGK2 | |
| Benzylphosphonic Acid SCHEMBL44318 | 0.75 | HPGD (0.60) | HPGDTSHRPGK1PGK2 | |
| SCHEMBL1932004 | 0.75 | NR1H4 (0.55) | NR3C1CYP2C19TSHRNR1H2NR1H3 | |
| SCHEMBL6560868 | 0.75 | NR3C1 (0.56) | NR3C1CNR2 | |
| SCHEMBL16353269 | 0.74 | PGK1 (0.49) | CYP2C19KDM4EHPGDPGK1PGK2 | |
| SCHEMBL7635507 | 0.74 | LMNA (0.48) | NR3C1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-4918064-A | TREATMENT OF ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | disclosed |