Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | PGK1 | P00558 | 5/20 | 0.42 |
| ▸ | PGK2 | P07205 | 5/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1804264 | 0.79 | CA2 (0.42) | CA12CA1CA2CA9 | |
| SCHEMBL13634482 | 0.79 | ALDH1A1 (0.48) | CA12CA1CA2CA9 | |
| SCHEMBL2641797 | 0.78 | ALDH1A1 (0.52) | ENPP2PGK1PGK2DGAT2 | |
| SCHEMBL16335457 | 0.76 | PGK1 (0.46) | ENPP2PGK1PGK2 | |
| SCHEMBL9512802 | 0.75 | NR3C1 (0.48) | PGK1PGK2 | |
| SCHEMBL797850 | 0.74 | CA2 (0.43) | CA12CA1CA2CA9 | |
| SCHEMBL3348892 | 0.74 | KEAP1 (0.54) | CA12CA1CA2CA9 | |
| SCHEMBL196635 | 0.74 | KMT2A (0.49) | CA12CA2CA9 | |
| SCHEMBL8169299 | 0.73 | ALDH1A1 (0.59) | — | |
| SCHEMBL3349309 | 0.73 | MAPT (0.41) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313002-B1 | Phenyl glycines for use in reducing neurotoxic injury | SEARLE & CO (US) | 1993-12-01 | — | — | EP | disclosed |
| US-4918064-A | TREATMENT OF ANOXIA OR ISCHEMIA | G. D. SEARLE & CO. (US) | 1990-04-17 | — | — | US | disclosed |
| EP-0313002-A2 | Phenyl glycines for use in reducing neurotoxic injury | G.D. Searle & Co. (US) | 1989-04-26 | — | — | EP | disclosed |