Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.53 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.53 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 10/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.47 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518145 | 0.82 | P4HTM (0.61) | BCL2L1MCL1PTGS2PTGS1P4HTM | |
| SCHEMBL9517033 | 0.80 | KDM4C (0.52) | ALKBH5FTO | |
| SCHEMBL10739775 | 0.75 | ALKBH2 (0.63) | ALKBH2ALKBH5FTOPTGS2PTGS1 | |
| SCHEMBL9515759 | 0.74 | P4HTM (0.58) | BCL2L1MCL1P4HTMEGFR | |
| SCHEMBL9516970 | 0.72 | BCL2L1 (0.48) | BCL2L1MCL1P4HTMEGFR | |
| SCHEMBL9517172 | 0.71 | BCL2L1 (0.50) | BCL2L1MCL1P4HTM | |
| SCHEMBL10746411 | 0.71 | PTGS2 (0.71) | ALKBH2ALKBH5FTOPTGS2PTGS1 | |
| SCHEMBL9515532 | 0.71 | P4HTM (0.61) | BCL2L1MCL1PTGS2PTGS1KAT6A | |
| SCHEMBL9517291 | 0.71 | BCL2L1 (0.47) | BCL2L1MCL1P4HTM | |
| SCHEMBL9517034 | 0.70 | LNPEP (0.44) | P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079466-A | 4-or 5-(sulphur) acylimino-and (inferior sulphur) amidopyridine and pyridine-N-oxide thereof | HOECHST AG (DE) | 1993-12-15 | — | — | CN | disclosed |
| EP-0567997-A1 | 4- or 5-(sulf)imido- and (sulfon)amidopyridines and their pyridine-N-oxides, process for their preparation and their use as pharmaceutical | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |