Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752170 | 0.86 | ADRA1A (0.56) | CTSKLMNASMN1; SMN2POLBGAA | |
| SCHEMBL8752169 | 0.81 | PKM (0.48) | CTSKLMNASMN1; SMN2POLBFFAR2 | |
| Mivotilate SCHEMBL8752155 | 0.80 | MAPT (0.43) | SMN1; SMN2POLBGAAFFAR2RAB9A | |
| SCHEMBL8752175 | 0.78 | L3MBTL1 (0.48) | LMNASMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL9521170 | 0.77 | SMN1; SMN2 (0.50) | LMNASMN1; SMN2GAAKMT2AADRA1A | |
| SCHEMBL9521395 | 0.76 | ADRA1A (0.41) | LMNASMN1; SMN2POLBGAAKMT2A | |
| SCHEMBL9521689 | 0.75 | POLB (0.45) | LMNASMN1; SMN2POLBKMT2AADRA1A | |
| SCHEMBL9520912 | 0.74 | MAPT (0.49) | LMNASMN1; SMN2POLBKMT2ARAB9A | |
| SCHEMBL1280159 | 0.74 | LMNA (0.51) | CTSKLMNASMN1; SMN2POLBGAA | |
| SCHEMBL9521064 | 0.73 | ADRA1A (0.60) | SMN1; SMN2GAAADRA1APDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366614-B1 | PHARMACEUTICALLY ACTIVE DITHIOKETENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1993-09-01 | — | — | EP | disclosed |
| US-5103013-A | For treating liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-04-07 | — | — | US | disclosed |