Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDX3X | O00571 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525680 | 0.86 | HTT (0.43) | ALDH1A1SMN1; SMN2MAPTKDM4ETHRB | |
| SCHEMBL9525725 | 0.86 | KMT2A (0.49) | ALDH1A1KDM4EABCG2 | |
| SCHEMBL9527660 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MAPTCYP1A2KDM4E | |
| SCHEMBL9523908 | 0.86 | HPGD (0.46) | ALDH1A1MAPTHDAC6THRBRECQL | |
| SCHEMBL9525178 | 0.86 | NPC1 (0.43) | ALDH1A1SMN1; SMN2MAPTCYP1A2KDM4E | |
| SCHEMBL9525121 | 0.84 | FLT3 (0.49) | ALDH1A1SMN1; SMN2KDM4ETHRB | |
| SCHEMBL9524899 | 0.83 | MAPT (0.50) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9524669 | 0.82 | KMT2A (0.50) | DDX3XALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9524816 | 0.81 | MEN1 (0.41) | ALDH1A1SMN1; SMN2MAPTKDM4E | |
| SCHEMBL9527795 | 0.80 | POLB (0.44) | ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |