Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | BRAF | P15056 | 3/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | TNNI3K | Q59H18 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525178 | 0.85 | NPC1 (0.43) | MAPTKMT2AMEN1KDM4EHTT | |
| SCHEMBL9525680 | 0.83 | HTT (0.43) | MAPTKMT2AL3MBTL1KDM4EHSP90AA1 | |
| SCHEMBL9523908 | 0.83 | HPGD (0.46) | MAPTKMT2AMEN1NPSR1HTT | |
| SCHEMBL9527700 | 0.83 | DDX3X (0.44) | MAPTKDM4EALDH1A1 | |
| SCHEMBL9527660 | 0.83 | ALDH1A1 (0.50) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL9525725 | 0.83 | KMT2A (0.49) | KMT2AMEN1KDM4EKDRRAB9A | |
| SCHEMBL9525121 | 0.81 | FLT3 (0.49) | KMT2AMEN1KDM4ERAB9AALDH1A1 | |
| SCHEMBL9524357 | 0.81 | KMT2A (0.56) | MAPTKMT2AMEN1L3MBTL1KDR | |
| SCHEMBL9524669 | 0.79 | KMT2A (0.50) | MAPTKMT2AMEN1L3MBTL1KDM4E | |
| SCHEMBL9524999 | 0.79 | RAB9A (0.44) | MAPTKMT2AMEN1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277791-B1 | CINNOLINE-CARBOXAMIDES AND PROCESS FOR THEIR PREPARATION | FARMITALIA CARLO ERBA S.r.l. (IT) | 1993-06-02 | — | — | EP | claimed |