Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525834 | 0.80 | KDM4E (0.44) | ALDH1A1KDM4EARGLAGAA | |
| SCHEMBL9525926 | 0.78 | CYP2C9 (0.31) | ALDH1A1KDM4EMAPTMAPK1 | |
| SCHEMBL7371784 | 0.73 | KDM4E (0.60) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL9530230 | 0.73 | MDM2 (0.41) | ALDH1A1KDM4EHPGDLMNAPOLB | |
| SCHEMBL7646365 | 0.72 | PDE5A (0.50) | ALDH1A1KDM4EARGLAGAA | |
| SCHEMBL9525541 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDARGLA | |
| SCHEMBL9526882 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL9702581 | 0.70 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL7646385 | 0.69 | PDE5A (0.44) | ALDH1A1KDM4EHPGDLMNAAR | |
| SCHEMBL9702565 | 0.69 | KDM4E (0.55) | ALDH1A1KDM4EHPGDLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |