Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529336 | 0.78 | OPRL1 (0.57) | CCR1OPRL1OPRM1SIGMAR1KMT2A | |
| SCHEMBL31284831 | 0.77 | CCR1 (0.53) | CCR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9844017 | 0.73 | SIGMAR1 (0.65) | CCR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9533670 | 0.73 | DRD2 (0.60) | CCR1OPRL1OPRM1DRD2 | |
| SCHEMBL8741960 | 0.73 | OPRL1 (0.55) | OPRL1OPRM1SIGMAR1KMT2AMEN1 | |
| SCHEMBL9529535 | 0.73 | DRD2 (0.60) | OPRM1OPRK1SIGMAR1CHRM1CHRM3 | |
| SCHEMBL31283836 | 0.72 | OPRL1 (0.51) | CCR1OPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL9529302 | 0.71 | SLC6A1 (0.61) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL1308581 | 0.71 | — | — | |
| SCHEMBL7964051 | 0.70 | CCR1 (0.52) | CCR1OPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |