Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.36 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530551 | 0.79 | RORC (0.44) | SMN1; SMN2ALDH1A1SAE1UBA2ABCC9 | |
| SCHEMBL9532610 | 0.79 | ALDH1A1 (0.42) | GAAADRA2AADRA2BADRA2CSMN1; SMN2 | |
| SCHEMBL10453701 | 0.77 | ABCC9 (0.46) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL9530153 | 0.74 | ALDH1A1 (0.42) | GAASMN1; SMN2ALDH1A1POLBHTT | |
| SCHEMBL9530625 | 0.72 | MAOA (0.44) | SMN1; SMN2ALDH1A1SAE1UBA2ABCC9 | |
| SCHEMBL9529457 | 0.72 | ABCC9 (0.46) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL8915586 | 0.72 | ABCC9 (0.46) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL10453762 | 0.71 | ABCC9 (0.45) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL10341391 | 0.70 | ABCC9 (0.45) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB | |
| SCHEMBL10341392 | 0.70 | ABCC9 (0.45) | TSHRSMN1; SMN2ALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |