Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 9/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10883634 | 0.81 | MEN1 (0.37) | CDK4CCND1HSD17B10 | |
| SCHEMBL9727098 | 0.76 | GABRA2 (0.40) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9727138 | 0.76 | ALDH1A1 (0.49) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10565417 | 0.74 | ALDH1A1 (0.48) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9194415 | 0.73 | GABRB3 (0.39) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10946405 | 0.73 | TRPV1 (0.53) | RAD51 | |
| SCHEMBL9194934 | 0.70 | GABRP (0.46) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL10679158 | 0.69 | GABRA2 (0.38) | GABRB3GABRA2GABRB2GABRPGABRD | |
| SCHEMBL9527504 | 0.69 | CYP3A4 (0.50) | GABRB3CDK4CCND1 | |
| SCHEMBL9727104 | 0.69 | P2RX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042937-C | Substituted fused pyrazolo compounds and their use as herbicides | ZENECA LTD (GB) | 1999-04-14 | — | — | CN | disclosed |
| EP-0257296-B1 | 4-CYANO(NITRO)-5-OXY(THIO)-PYRAZOLE DERIVATIVES | BAYER AG (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| US-4804398-A | 1-aryl-4-cyano-5-halogenopyrazoles, composition containing them, and method of using them as selective herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4770692-A | 4-cyano(nitro)-5-oxy(thio)-pyrazole derivatives, composition containing them, and herbicidal and plant growth regulating methods of using them | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| EP-0257296-A1 | 4-Cyano(nitro)-5-oxy(thio)-pyrazole derivatives | BAYER AG (DE) | 1988-03-02 | — | — | EP | disclosed |