Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GABRB3 | P28472 | 9/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.37 |
| ▸ | GABRD | O14764 | 3/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10565417 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPTGABRB3GABRA2GABRB2 | |
| SCHEMBL7454623 | 0.82 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9727098 | 0.81 | GABRA2 (0.40) | SMN1; SMN2GABRB3GABRA2GABRB2CDK4 | |
| SCHEMBL9194415 | 0.78 | GABRB3 (0.39) | SMN1; SMN2GABRB3GAAGABRA2GABRB2 | |
| SCHEMBL9194934 | 0.77 | GABRP (0.46) | ALDH1A1MAPTKDM4EGABRB3GAA | |
| SCHEMBL9530253 | 0.76 | GABRB3 (0.40) | GABRB3GABRA2GABRB2CDK4CCND1 | |
| SCHEMBL4338380 | 0.74 | MAPT (0.63) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9727170 | 0.73 | GABRB3 (0.39) | SMN1; SMN2GABRB3KMT2AHTTMEN1 | |
| SCHEMBL4338425 | 0.71 | ALKBH5 (0.64) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL9464693 | 0.70 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162528-A | Pre- and post-emergence; phytaphthora in tomato plants; rice and wheat | BAYER AKTIENGESELLSCHAFT (DE) | 1992-11-10 | — | — | US | disclosed |
| US-5028717-A | Herbicidal and fungicidal agents based on substituted pyrazolin-5-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | disclosed |
| US-4909827-A | Containing a C6-10 aryl group substituted in position 1 | BAYER AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |