SCHEMBL9533477

SCHEMBL9533477

O=CC1CC(=O)c2cc(Cl)c(Cl)cc21

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9533467 0.70 KDM4E (0.33) KDM4EMAPK1AHR
SCHEMBL2354458 0.69 S100A4 (0.41) KDM4EMAPK1
SCHEMBL8561999 0.69 CHRNB2 (0.32) KDM4E
Hydrochloric Acid SCHEMBL8565575 0.68 ALDH1A1 (0.35) KDM4E
SCHEMBL25909872 0.66
SCHEMBL8052912 0.61 AHR (0.45) KDM4EMAPK1AHR
SCHEMBL8065508 0.60 TRPM5 (0.42)
SCHEMBL8564785 0.60 CHRNB2 (0.31)
SCHEMBL9818879 0.59 PBRM1 (0.58) KDM4EMAPK1
SCHEMBL9819094 0.59 PBRM1 (0.58) KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0356247-B1 ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES Sankyo Company Limited (JP) 1993-03-17 EP disclosed