Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | USP10 | Q14694 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535630 | 0.76 | USP7 (0.53) | ALDH1A1MAPK14MAPK13SLC6A4MAPT | |
| SCHEMBL576377 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK14MAPK13USP10USP7 | |
| SCHEMBL30452220 | 0.75 | ALDH1A1 (0.46) | ALDH1A1MAPK14MAPK13USP10USP7 | |
| SCHEMBL1339061 | 0.75 | SLC6A4 (0.51) | ALDH1A1SLC6A2SLC6A4MAPTPDE7A | |
| SCHEMBL9535502 | 0.75 | MAPT (0.46) | ALDH1A1MAPK14KDM4EMAPTHPGD | |
| SCHEMBL9538632 | 0.75 | G6PD (0.58) | ALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL9535423 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPK14SLC6A2SLC6A4KDM4E | |
| SCHEMBL9535342 | 0.74 | PTGS2 (0.57) | ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9180206 | 0.73 | NPC1 (0.41) | ALDH1A1SLC6A2SLC6A4KDM4EMAPT | |
| SCHEMBL9534376 | 0.73 | MAPK14 (0.46) | ALDH1A1MAPK14KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |