Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533937 | 0.90 | ALDH1A1 (0.50) | ALDH1A1MAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL9536170 | 0.90 | MAPT (0.52) | ALDH1A1MAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL9537454 | 0.88 | GHSR (0.50) | ALDH1A1SMN1; SMN2GHSRCYP1A2CYP3A4 | |
| SCHEMBL9533918 | 0.87 | MAPT (0.64) | ALDH1A1MAPTTP53MAPK1SMN1; SMN2 | |
| SCHEMBL9533388 | 0.80 | TSHR (0.51) | ALDH1A1MAPTCYP1A2GAACYP2C19 | |
| SCHEMBL5242546 | 0.80 | KMT2A (0.56) | MAPK1SMN1; SMN2GAAPTGS2 | |
| SCHEMBL27495331 | 0.78 | KMT2A (0.55) | ALDH1A1MAPK1SMN1; SMN2GAAPTGS2 | |
| SCHEMBL12585052 | 0.78 | MAPK1 (0.79) | ALDH1A1TP53MAPK1SMN1; SMN2GHSR | |
| SCHEMBL9535701 | 0.77 | KMT2A (0.54) | MAPK1SMN1; SMN2GAAPTGS2 | |
| SCHEMBL9533884 | 0.77 | KMT2A (0.59) | ALDH1A1MAPTTP53SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |