Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540523 | 0.88 | HTR1A (0.48) | MAPTMEN1KMT2AHTR2AHTR2C | |
| SCHEMBL9535969 | 0.81 | AR (0.48) | MEN1KMT2AHTR2AHTR2CDRD2 | |
| SCHEMBL9537473 | 0.77 | KDM4E (0.46) | HTR2ADRD2HTR1A | |
| SCHEMBL9537865 | 0.76 | SIGMAR1 (0.53) | MAPTHTR2ADRD2HTR1A | |
| SCHEMBL9538643 | 0.76 | KDM4E (0.45) | MAPTHTR2ADRD4DRD2HTR1A | |
| SCHEMBL9536766 | 0.76 | ALDH1A1 (0.42) | DRD2GRIN2B | |
| SCHEMBL9536717 | 0.71 | HTR1A (0.38) | HTR2ADRD2ADRB1HTR1A | |
| SCHEMBL9537328 | 0.68 | SIGMAR1 (0.46) | DRD4DRD2HTR1A | |
| SCHEMBL10646895 | 0.68 | DRD2 (0.49) | HTR2ADRD2HTR1A | |
| SCHEMBL20231203 | 0.68 | MAPT (0.63) | MAPTNPSR1KMT2ADRD2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254623-B1 | AMINOALKYLTHIO TRIAZOLOPYRIDINE OR TRIAZOLOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY USEFUL AS ANTALGICS | LABORATOIRES UPSA (FR) | 1993-06-09 | — | — | EP | disclosed |