Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537473 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1DRD2ADRA1ALMNA | |
| SCHEMBL28070630 | 0.86 | ADRA1B (0.46) | DRD2ADRA1ADRD3SIGMAR1HTR1A | |
| SCHEMBL9535969 | 0.86 | AR (0.48) | ALDH1A1DRD2ADRA1ADRD3LMNA | |
| SCHEMBL9540523 | 0.81 | HTR1A (0.48) | ALDH1A1POLBDRD2DRD3MAPT | |
| SCHEMBL9535966 | 0.76 | MAPT (0.45) | DRD2MAPTDRD4HTR1AHTR2A | |
| SCHEMBL9537865 | 0.74 | SIGMAR1 (0.53) | ALDH1A1TSHRDRD2ADRA1ADRD3 | |
| SCHEMBL9536766 | 0.74 | ALDH1A1 (0.42) | KDM4EALDH1A1POLBTSHRDRD2 | |
| SCHEMBL9535704 | 0.72 | KDM4E (0.59) | KDM4EALDH1A1DRD2DRD3LMNA | |
| SCHEMBL10646895 | 0.71 | DRD2 (0.49) | DRD2DRD3SIGMAR1HTR1AHTR2A | |
| SCHEMBL4256755 | 0.70 | KDM4E (0.63) | KDM4EALDH1A1POLBTSHRDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254623-B1 | AMINOALKYLTHIO TRIAZOLOPYRIDINE OR TRIAZOLOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY USEFUL AS ANTALGICS | LABORATOIRES UPSA (FR) | 1993-06-09 | — | — | EP | disclosed |