Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | USP14 | P54578 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14388165 | 0.85 | USP14 (0.42) | BCHEKDM4EALDH1A1USP14 | |
| SCHEMBL7332383 | 0.82 | HTR4 (0.43) | HTR1ADRD2 | |
| SCHEMBL2607044 | 0.82 | SMN1; SMN2 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1 | |
| SCHEMBL13036975 | 0.81 | BCHE (0.44) | BCHEKDM4EALDH1A1HTR7HTR1A | |
| SCHEMBL13036977 | 0.80 | SMN1; SMN2 (0.45) | BCHEKDM4EALDH1A1HTR7HTR1A | |
| SCHEMBL6964631 | 0.78 | SLC6A1 (0.53) | DRD2 | |
| SCHEMBL8553634 | 0.77 | POLB (0.45) | KDM4EALDH1A1 | |
| SCHEMBL11709792 | 0.77 | LMNA (0.45) | KDM4EALDH1A1 | |
| SCHEMBL11712424 | 0.77 | LMNA (0.45) | KDM4EALDH1A1 | |
| SCHEMBL11717512 | 0.77 | LMNA (0.45) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003725-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |