Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 9/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TYMS | P04818 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | TLR4 | O00206 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252979 | 0.93 | DHFR (0.66) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| Folic Acid SCHEMBL28187096 | 0.92 | KDM4E (0.68) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL25630863 | 0.92 | DHFR (0.63) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL17011394 | 0.92 | DHFR (0.75) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL29578377 | 0.92 | DHFR (0.75) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| Folic Acid SCHEMBL28083228 | 0.92 | KDM4E (0.67) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL17234844 | 0.91 | KDM4E (0.63) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL14008776 | 0.91 | KDM4E (0.63) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| SCHEMBL12243056 | 0.91 | KDM4E (0.63) | DHFRKDM4EMEN1ALDH1A1TYMS | |
| Folic Acid SCHEMBL3878 | 0.91 | KDM4E (0.73) | DHFRKDM4EMEN1ALDH1A1TYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145785-A1 | BENZIMIDAZOLE DERIVATIVES AND SALTS THEREOF EXHIBITING AN ANTI-GERIATRIC EFFECT | ФАРБЕР, Борис Славинович | 2021-07-22 | — | — | WO | disclosed |
| US-20140079757-A1 | ORAL DRUG DELIVERY FORMULATIONS | BROWN RUDNICK LLP | 2014-03-20 | — | — | US | disclosed |
| US-20120058097-A1 | COMPOSITIONS INCLUDING A SODIUM CHANNEL BLOCKER AND A B VITAMIN MOLECULE AND METHODS OF USE THEREOF | MS THERAPEUTICS LIMITED (GB) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058097-A1 | COMPOSITIONS INCLUDING A SODIUM CHANNEL BLOCKER AND A B VITAMIN MOLECULE AND METHODS OF USE THEREOF | CACNA1B, KCNMB1, KCNB2 | DHFR 702/4885KDM4E 2159/4885MEN1 2557/4885 |
| US-20140079757-A1 | ORAL DRUG DELIVERY FORMULATIONS | PGF, MMP1, MMP26 | DHFR 448/4885KDM4E 1603/4885MEN1 683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.