Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TYMS | P04818 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | DHFR | P00374 | 9/20 | 0.62 |
| ▸ | TLR4 | O00206 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243056 | 1.00 | KDM4E (0.63) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| SCHEMBL14008776 | 1.00 | KDM4E (0.63) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL28622715 | 0.94 | KDM4E (0.70) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| SCHEMBL19543324 | 0.94 | DHFR (0.56) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL6470174 | 0.93 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL3878 | 0.93 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL12148554 | 0.93 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL29677832 | 0.93 | KDM4E (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| SCHEMBL26422283 | 0.92 | DHFR (0.73) | KDM4EMEN1ALDH1A1TYMSPOLB | |
| Folic Acid SCHEMBL23388805 | 0.92 | KDM4E (0.72) | KDM4EMEN1ALDH1A1TYMSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159455-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| WO-2023076586-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| WO-2023076534-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | SENSORIUM THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |
| US-9884886-B2 | Disulfide masked prodrug compositions and methods | MERCK SHARP & DOHME (US) | 2018-02-06 | — | — | US | disclosed |
| US-20150315226-A1 | DISULFIDE MASKED PRODRUG COMPOSITIONS AND METHODS | MERCK SHARP & DOHME CORP. (US) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159455-A1 | DELIVERY OF THERAPEUTIC ALKALOID COMPOUNDS | PNMT, HNMT, NNMT | KDM4E 2549/4885MEN1 163/4885ALDH1A1 1109/4885 |
| US-20150315226-A1 | DISULFIDE MASKED PRODRUG COMPOSITIONS AND METHODS | GSS, GSTP1, GSTM2 | KDM4E 4148/4885MEN1 3802/4885ALDH1A1 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.