Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28109363 | 0.88 | LMNA (0.49) | GAACYP3A4ALOX5TSHRALDH1A1 | |
| SCHEMBL1504425 | 0.88 | PTGS2 (0.58) | GAACYP3A4PTGS2ALDH1A1MAPT | |
| SCHEMBL27802288 | 0.88 | FAAH (0.51) | GAACYP3A4ALOX5TSHRPTGS2 | |
| SCHEMBL14153913 | 0.87 | GAA (0.50) | GAACYP3A4ALOX5TSHRPTGS2 | |
| SCHEMBL14108086 | 0.86 | PTGS2 (0.65) | GAACYP3A4PTGS2ALDH1A1MAPT | |
| SCHEMBL14273152 | 0.84 | NOTUM (0.49) | GAAALDH1A1SMN1; SMN2HTTKMT2A | |
| SCHEMBL14108137 | 0.84 | ALDH1A1 (0.49) | GAACYP3A4ALOX5TSHRPTGS2 | |
| SCHEMBL7154018 | 0.84 | MGLL (0.46) | GAAALDH1A1MAPTRAD51KDM4E | |
| SCHEMBL28849976 | 0.83 | BCAT2 (0.46) | GAAALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL14108129 | 0.82 | EPHX2 (0.51) | GAAALDH1A1MAPTCYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236939-A | Substituted 1,3,4-oxa(thia)diazolinones process for their preparation and their use of combating endoparasites | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| US-4420308-A | Process for the production of reserve effects on polyester textiles and polyester/cellulose mixed fibre textiles: discharge printing with disperse azo dye with alkyl or alkoxy carbonyl, cyand and hydroxy phenyl group | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-12-13 | — | — | US | disclosed |