Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645833 | 0.87 | EGFR (0.43) | EGFRPPARGPPARAALDH1A1LMNA | |
| SCHEMBL9558477 | 0.84 | PLA2G2A (0.45) | SLC1A1PPARGPPARAALDH1A1LMNA | |
| SCHEMBL9645703 | 0.84 | L3MBTL1 (0.42) | SLC1A1LMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9645652 | 0.81 | CCKBR (0.40) | EGFRPPARGPPARAALDH1A1LMNA | |
| SCHEMBL9645639 | 0.77 | L3MBTL1 (0.46) | SLC1A1CYP1A2CYP3A4CYP2C19POLB | |
| SCHEMBL7075493 | 0.74 | ALDH1A1 (0.43) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6823148 | 0.74 | MAPT (0.57) | ALDH1A1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27218104 | 0.70 | PRNP (0.49) | ALDH1A1LMNAGFERPOLBSMN1; SMN2 | |
| SCHEMBL27218106 | 0.70 | PRNP (0.49) | ALDH1A1LMNAGFERPOLBSMN1; SMN2 | |
| SCHEMBL9644879 | 0.70 | MMP2 (0.41) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508004-A1 | Phenylsulfonylalkanoic acid compounds | Kissei Pharmaceutical Co., Ltd. (JP) | 1992-10-14 | — | — | EP | disclosed |
| US-5145869-A | Treatment of irritable bowel syndrome, dyskinesia, pancreatist; hormone inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-09-08 | — | — | US | disclosed |