SCHEMBL9560140

SCHEMBL9560140

CCCc1c(-c2cc(Br)c(O)c(Br)c2)cc(Br)c(O)c1Br

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
CYP3A4 P08684 2/20 0.34
TSHR P16473 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
ESR1 P03372 1/20 0.34
PTPN1 P18031 4/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALOX12 P18054 1/20 0.33
CASP1 P29466 1/20 0.33
RECQL P46063 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GABRA1 P14867 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560533 0.69 ALOX5 (0.41) ESR1ALOX15ALOX12GABRA1GABRB2
SCHEMBL542182 0.69 CYP3A4 (0.46) CRHBPCRHR2CA1CA2CA4
SCHEMBL6232080 0.67 PGAM1 (0.39) CA1CA2CA4CA6PTPN1
SCHEMBL5587159 0.66 PTPN1 (0.50) CA1CA2CA4CA6PTPN1
SCHEMBL28102507 0.65 PTGS2 (0.40) CYP3A4PTPN1ALDH1A1HPGDCNR1
SCHEMBL18371594 0.65 HPGD (0.39) TSHRTDP1ESR1PTPN1ALDH1A1
SCHEMBL5587220 0.65 CA1 (0.42) CA1CA2CA4CA6PTPN1
SCHEMBL581997 0.65 CRHBP (0.70) CRHBPCRHR2CA1CA2CA4
SCHEMBL19729139 0.64 PTPN1 (0.38) CA1CA2CA4CA6CYP3A4
SCHEMBL11703019 0.64 CA1 (0.46) CA1CA2CA4CA6PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113242886-B Thermoplastic composition for laser direct structuring 三菱化学株式会社 2024-02-09 CN disclosed
CN-113423774-B Thermoplastic composition for laser direct structuring MEP欧洲有限公司 2023-12-15 CN disclosed
CN-116134174-A Thermoplastic composition for laser direct structuring MEP欧洲有限公司 2023-05-16 CN disclosed
EP-0277804-B1 POLYCARBONATE FILMS EFFECTIVE AS OPTICAL PHASE RETARDERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-09-29 EP disclosed
US-5061042-A Phase retarder and liquid crystal display using the same SUMITOMO CHEMICAL CO., LTD. (JP) 1991-10-29 US disclosed
US-4722809-A BLEND WITH HAOLGENATED AROMATIC POLYCARBONATE THE DOW CHEMICAL COMPANY (US) 1988-02-02 US disclosed
EP-0016791-A4 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE. GEN ELECTRIC (US) 1980-10-15 EP disclosed
EP-0016791-A1 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE GENERAL ELECTRIC COMPANY (US) 1980-10-15 EP disclosed
WO-1980000084-A1 DUCTILE AND SOLVENT RESISTANT POLYCARBONATE COMPOSITIONS HAVING IMPROVED FLAME RESISTANCE GEN ELECTRIC (US) 1980-01-24 WO disclosed