SCHEMBL9563945

SCHEMBL9563945

C=CC(=O)OCCNC(=O)OC(C)C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
HTT P42858 2/20 0.46
LMNA P02545 1/20 0.46
TSHR P16473 8/20 0.46
MAPK1 P28482 2/20 0.45
MEN1 O00255 1/20 0.45
CYP1A2 P05177 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
KMT2A Q03164 1/20 0.45
HPGD P15428 1/20 0.44
ALDH1A1 P00352 4/20 0.44
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
CYP3A4 P08684 2/20 0.44
HSD17B10 Q99714 1/20 0.44
ALOX15 P16050 1/20 0.38
THRB P10828 2/20 0.38
CHRNB2 P17787 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9563959 0.91 SMN1; SMN2 (0.41) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL23225387 0.91 SMN1; SMN2 (0.41) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL25993937 0.86 ACHE (0.46) SMN1; SMN2HTTTSHRMAPK1MEN1
SCHEMBL18352593 0.86 SMN1; SMN2 (0.49) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL12922582 0.86 TSHR (0.45) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL23448982 0.85 TSHR (0.44) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL26078407 0.84 TSHR (0.45) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL18354885 0.83 HCAR2 (0.47) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL20202285 0.83 TSHR (0.41) SMN1; SMN2HTTLMNATSHRMAPK1
SCHEMBL30341925 0.83 TSHR (0.44) SMN1; SMN2HTTLMNATSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0530141-A1 Radiation curable composition with high temperature oil resistance CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound FUJIFILM CORPORATION (JP) 2024-01-16 US disclosed
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-10-10 US disclosed
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings META PLATFORMS TECHNOLOGIES, LLC (US) 2023-08-08 US disclosed
US-11518916-B2 Lens adhesive, cemented lens, and imaging module FUJIFILM CORPORATION (JP) 2022-12-06 US disclosed
US-20220153895-A1 SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2022-05-19 US disclosed
WO-2022104137-A1 SUBSTITUTED PROPANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS FACEBOOK TECHNOLOGIES, LLC (US) 2022-05-19 WO disclosed
US-20220153693-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2022-05-19 US disclosed
US-20210155581-A1 AROMATIC SUBSTITUTED ETHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20210155599-A1 AROMATIC SUBSTITUTED ALKANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20210155584-A1 AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2021-05-27 US disclosed
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
US-20200355997-A1 THIANTHRENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS META PLATFORMS TECHNOLOGIES, LLC 2020-11-12 US disclosed
US-20200325367-A1 LENS ADHESIVE, CEMENTED LENS, AND IMAGING MODULE FUJIFILM CORPORATION (JP) 2020-10-15 US disclosed
EP-0530141-A1 Radiation curable composition with high temperature oil resistance CIBA-GEIGY AG (CH) 1993-03-03 EP disclosed
US-5183831-A Acylated polyurethanes CIBA-GEIGY CORPORATION (US) 1993-02-02 US disclosed
US-5047261-A Monoacrylated Alkylene Dicarbonate SOCIETE NATIONALE DES POURDRES ET EXPLOSIFS (FR) 1991-09-10 US disclosed
EP-0263749-A1 Process for the preparation of radiocrosslinked coatings SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1988-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200325367-A1 LENS ADHESIVE, CEMENTED LENS, AND IMAGING MODULE SP1, SPOP, SMC2 SMN1; SMN2 3208/4885HTT 3689/4885LMNA 1584/4885
US-20220153693-A1 SUBSTITUTED MONO- AND POLY-PHENYL-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS PARG, PARN, PCBP1 SMN1; SMN2 3172/4885HTT 874/4885LMNA 1442/4885
US-20200355997-A1 THIANTHRENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS TST, SMO, BRAP SMN1; SMN2 2734/4885HTT 419/4885LMNA 4146/4885
US-20200354311-A1 FLUORENE DERIVATIZED MONOMERS AND POLYMERS FOR VOLUME BRAGG GRATINGS RHOA, PARG, LSG1 SMN1; SMN2 791/4885HTT 1089/4885LMNA 1160/4885
US-11718580-B2 Fluorene derivatized monomers and polymers for volume Bragg gratings RHOA, PARG, LSG1 SMN1; SMN2 791/4885HTT 1089/4885LMNA 1160/4885
US-11873426-B2 Curable composition, cured product, optical member, lens, and compound RB1, CCNO, SPOP SMN1; SMN2 2646/4885HTT 2478/4885LMNA 421/4885
US-20210155584-A1 AROMATIC SUBSTITUTED METHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS SMAD2, MAFG, MYO1G SMN1; SMN2 1698/4885HTT 884/4885LMNA 2632/4885
US-20210155599-A1 AROMATIC SUBSTITUTED ALKANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS SMAD2, ALK, SMAD3 SMN1; SMN2 2029/4885HTT 1401/4885LMNA 2311/4885
US-20210155581-A1 AROMATIC SUBSTITUTED ETHANE-CORE MONOMERS AND POLYMERS THEREOF FOR VOLUME BRAGG GRATINGS SMAD2, KDM2A, SMAD3 SMN1; SMN2 2895/4885HTT 437/4885LMNA 2661/4885
US-11780819-B2 Aromatic substituted alkane-core monomers and polymers thereof for volume Bragg gratings SMAD2, ALK, SMAD3 SMN1; SMN2 2029/4885HTT 1401/4885LMNA 2311/4885
US-11518916-B2 Lens adhesive, cemented lens, and imaging module SP1, SPOP, SMC2 SMN1; SMN2 3208/4885HTT 3689/4885LMNA 1584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.