Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | FAP | Q12884 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853236 | 0.88 | PKM (0.60) | KDM4EMAPK1EPHX1NPC1 | |
| SCHEMBL7855232 | 0.86 | FAP (0.46) | FAPKDM4EMAPK1EPHX1ALDH1A1 | |
| SCHEMBL7843881 | 0.86 | FAP (0.46) | FAPKDM4EMAPK1EPHX1ALDH1A1 | |
| SCHEMBL7855259 | 0.83 | NPC1 (0.52) | FAPKDM4ENPC1RAB9A | |
| SCHEMBL7843748 | 0.82 | EPHX2 (0.60) | EPHX2FAPKDM4EMAPK1EPHX1 | |
| SCHEMBL7855299 | 0.80 | CYP2C19 (0.57) | FAPKDM4EMAPK1TSHRLMNA | |
| SCHEMBL7852927 | 0.79 | FAP (0.54) | FAPKDM4EMAPK1ALDH1A1TSHR | |
| SCHEMBL7844467 | 0.79 | NPC1 (0.65) | KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL7845289 | 0.79 | ACE (0.59) | TSHR | |
| SCHEMBL13230 | 0.77 | CA2 (0.67) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5271187-A | — | — | None | — | — | JP | disclosed |
| JP-H05271187-A | PYRROLIDINE DERIVATIVE OR ITS PHARMACOLOGICALLY ACCEPTABLE SALT | MICROBIAL CHEM RES FOUND | 1993-10-19 | — | — | JP | disclosed |