Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 13/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.38 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9564721 | 0.75 | HTR2C (0.39) | HTR2CROCK2HTR2BHTR2A | |
| SCHEMBL8988580 | 0.75 | HRH3 (0.43) | HTR2CROCK2HTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL8988698 | 0.73 | ITGB3 (0.42) | ROCK2PTPN1 | |
| SCHEMBL10691676 | 0.70 | HTR2C (0.60) | HTR2CROCK2HTR2B | |
| SCHEMBL8415369 | 0.68 | OPRD1 (0.35) | HTR2CHTR2BHTR2A | |
| SCHEMBL13410161 | 0.68 | ROCK2 (0.49) | HTR2CROCK2 | |
| SCHEMBL8988516 | 0.66 | HRH3 (0.40) | HTR2CROCK2HTR2BHTR2A | |
| SCHEMBL7351360 | 0.65 | HTR2C (0.56) | HTR2CROCK2 | |
| SCHEMBL8988588 | 0.64 | ITGB3 (0.49) | HTR2C | |
| SCHEMBL8571534 | 0.63 | P2RX7 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |