Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.37 |
| ▸ | COPS5 | Q92905 | 2/20 | 0.37 |
| ▸ | PTPRC | P08575 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812825 | 0.79 | TDP2 (0.41) | PTPRCCTSLCTSSPTPN13TDP1 | |
| SCHEMBL687504 | 0.75 | PSMD14 (0.52) | PSMD14COPS5PTPRCCTSLCTSS | |
| SCHEMBL29268766 | 0.74 | PTGS2 (0.44) | PTPRCCTSLCTSSPTPN13TDP1 | |
| SCHEMBL8394956 | 0.73 | KDM4E (0.62) | TDP1MEN1BLMKMT2AGAA | |
| SCHEMBL31543749 | 0.72 | KDM4E (0.54) | PSMD14COPS5PTPRCCTSLCTSS | |
| SCHEMBL586397 | 0.71 | TP53 (0.39) | TDP1BLMKDM4EGMNNLMNA | |
| SCHEMBL3195117 | 0.70 | SQOR (0.38) | TDP1TDP2NSD2ABL1PLCG1 | |
| SCHEMBL379708 | 0.70 | KDM4E (0.32) | KDM4ELMNATP53ALOX15HTT | |
| SCHEMBL2911431 | 0.69 | PSMD14 (0.46) | PSMD14COPS5PTPRCCTSLCTSS | |
| SCHEMBL131503 | 0.68 | KDM4E (0.64) | TDP1MEN1BLMKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | claimed |
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |