Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254265 | 0.74 | KDM4E (0.49) | CYP1A2PKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL9565640 | 0.72 | L3MBTL1 (0.36) | CYP1A2CYP3A4CYP2C9CYP2C19PKM | |
| SCHEMBL9565639 | 0.71 | L3MBTL1 (0.41) | CYP1A2PKMSMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL812825 | 0.69 | TDP2 (0.41) | CYP3A4SMN1; SMN2GAATSHR | |
| SCHEMBL9256751 | 0.69 | ALDH1A1 (0.36) | PKMSMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL9565616 | 0.67 | PSMD14 (0.37) | CYP3A4SMN1; SMN2GAATSHR | |
| SCHEMBL23730779 | 0.66 | HTR2C (0.37) | PKMSMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL27690425 | 0.66 | L3MBTL1 (0.44) | CYP1A2PKMSMN1; SMN2L3MBTL1GAA | |
| SCHEMBL8394956 | 0.66 | KDM4E (0.62) | CYP3A4CYP2C9SMN1; SMN2L3MBTL1GAA | |
| SCHEMBL9986851 | 0.66 | KDM4E (0.44) | CYP1A2PKMSMN1; SMN2L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | claimed |
| US-5240926-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1993-08-31 | — | — | US | disclosed |
| EP-0529468-A1 | Substituted pyridyltriazines, process for their preparation, their use and intermediates | BAYER AG (DE) | 1993-03-03 | — | — | EP | disclosed |