Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 6/20 | 0.43 |
| ▸ | MPL | P40238 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.41 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566461 | 0.88 | L3MBTL1 (0.49) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9566634 | 0.85 | ADORA1 (0.48) | MEN1KMT2AKDM4EMAPTKCNQ3 | |
| SCHEMBL10483353 | 0.84 | SIRT2 (0.55) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL9566514 | 0.83 | CSNK1D (0.45) | KDM4EMAPTGABRPGABRDGABRA1 | |
| SCHEMBL9566552 | 0.83 | GABRP (0.48) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9566580 | 0.83 | L3MBTL1 (0.42) | KMT2ANPC1RAB9AKCNQ3KCNQ2 | |
| SCHEMBL9566563 | 0.82 | TYK2 (0.49) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL9566531 | 0.82 | HDAC1 (0.48) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9566459 | 0.81 | JAK2 (0.45) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL10483488 | 0.81 | L3MBTL1 (0.45) | KMT2AMPLNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | claimed |
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |
| US-4874762-A | TREATING DEMENTIA | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-17 | — | — | US | disclosed |