Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 3/20 | 0.49 |
| ▸ | JAK2 | O60674 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566459 | 0.87 | JAK2 (0.45) | TYK2JAK2NPC1RAB9ALCK | |
| SCHEMBL9566634 | 0.84 | ADORA1 (0.48) | TYK2JAK2MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10483371 | 0.83 | JAK2 (0.41) | TYK2JAK2NPC1RAB9ALCK | |
| SCHEMBL9566616 | 0.82 | ALDH1A1 (0.46) | TYK2JAK2NPC1RAB9AMAPT | |
| SCHEMBL9566461 | 0.82 | L3MBTL1 (0.49) | NPC1RAB9AKMT2AGABRPGABRD | |
| SCHEMBL9566552 | 0.81 | GABRP (0.48) | NPC1RAB9AMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL10483488 | 0.81 | L3MBTL1 (0.45) | TYK2JAK2NPC1RAB9ALCK | |
| SCHEMBL9566580 | 0.81 | L3MBTL1 (0.42) | TYK2JAK2NPC1RAB9AKMT2A | |
| SCHEMBL10483546 | 0.79 | LMNA (0.45) | NPC1RAB9AMAPTKMT2AGABRP | |
| SCHEMBL10483353 | 0.78 | SIRT2 (0.55) | NPC1RAB9AKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563386-A1 | ANTICANCER COMPOSITION AND COMPOUND | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-10-06 | — | — | EP | disclosed |