Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 12/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292630 | 0.84 | MEN1 (0.48) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL9519673 | 0.81 | NOS3 (0.41) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL13803190 | 0.79 | LNPEP (0.48) | NOS3NOS1NOS2LNPEPKDM4E | |
| SCHEMBL2921165 | 0.78 | ALDH1A1 (0.40) | KDM4EMAPTKDM5AKDM4CKDM5B | |
| SCHEMBL9566847 | 0.78 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL2637576 | 0.77 | CCR1 (0.52) | KDM4EMAPTKDM5AKDM4CKDM5B | |
| SCHEMBL9517034 | 0.77 | LNPEP (0.44) | LNPEPKDM4EMAPTKDM5AKDM4C | |
| Acetic Acid SCHEMBL11369793 | 0.76 | GCK (0.51) | LNPEPKDM4E | |
| Hydrochloric Acid SCHEMBL6850653 | 0.76 | CCR1 (0.50) | KDM4EMAPTKDM5AKDM4CKDM5B | |
| SCHEMBL9566819 | 0.76 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |