Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566784 | 0.88 | LMNA (0.44) | SMN1; SMN2LMNATAAR1NPC1GAA | |
| SCHEMBL9566730 | 0.86 | KDM4E (0.45) | LMNATAAR1NPC1GAARAB9A | |
| SCHEMBL9517034 | 0.82 | LNPEP (0.44) | LNPEP | |
| SCHEMBL9566847 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2EPHX1 | |
| SCHEMBL9566774 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL9566819 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL2243907 | 0.72 | SMN1; SMN2 (0.63) | SMN1; SMN2TAAR1NPC1GAARAB9A | |
| SCHEMBL9566834 | 0.72 | LOXL2 (0.41) | — | |
| SCHEMBL9517033 | 0.72 | KDM4C (0.52) | — | |
| SCHEMBL9566858 | 0.71 | HPGD (0.43) | SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533130-A1 | 2-Hydroxymethylpyridines, the corresponding pyridine-N-oxides and derivatives thereof, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-24 | — | — | EP | disclosed |