SCHEMBL9568658

SCHEMBL9568658

C=CC(=O)Nc1ccccc1NS(C)(=O)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 3/20 0.49
KMT2A Q03164 2/20 0.47
TSHR P16473 2/20 0.46
MAPK3 P27361 1/20 0.45
KEAP1 Q14145 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTPN1 P18031 1/20 0.44
PTPN11 Q06124 1/20 0.44
RORC P51449 2/20 0.44
KDM4E B2RXH2 3/20 0.43
HTT P42858 2/20 0.43
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
MEN1 O00255 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
EP300 Q09472 1/20 0.42
KAT2B Q92831 1/20 0.42
KAT8 Q9H7Z6 1/20 0.42
NFE2L2 Q16236 1/20 0.42
GAA P10253 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568784 0.84 PSIP1 (0.50) TGM2PTPN1PTPN11RORCHPGD
SCHEMBL31228347 0.84 TGM2 (0.65) TGM2MAPK3PTPN1PTPN11KDM4E
SCHEMBL613090 0.84 TGM2 (0.65) TGM2MAPK3PTPN1PTPN11KDM4E
SCHEMBL9568726 0.81 SMN1; SMN2 (0.52) TGM2KMT2ATSHRHTTALDH1A1
SCHEMBL9568811 0.79 LMNA (0.70) TGM2TSHRKEAP1L3MBTL1ALDH1A1
SCHEMBL27272493 0.79 TSHR (0.61) KMT2ATSHRKEAP1L3MBTL1KDM4E
SCHEMBL17524758 0.79 TGM2 (0.55) TGM2MAPK3PTPN1PTPN11RORC
SCHEMBL29904739 0.78 KEAP1 (0.65) KMT2ATSHRKEAP1L3MBTL1KDM4E
SCHEMBL2068498 0.78 KEAP1 (0.65) KMT2ATSHRKEAP1L3MBTL1KDM4E
SCHEMBL397784 0.77 ALDH1A1 (0.53) TGM2KMT2AKEAP1L3MBTL1PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544264-A1 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1993-06-02 EP disclosed