Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577133 | 0.81 | KEAP1 (0.57) | CA1CA2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9577203 | 0.75 | MCL1 (0.43) | CA1CA2 | |
| SCHEMBL7589405 | 0.72 | MEN1 (0.59) | CA1CA2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL7595736 | 0.72 | SLC40A1 (0.61) | CA1CA2 | |
| SCHEMBL9577208 | 0.72 | PTGES2 (0.41) | CA1CA2MEN1KMT2A | |
| SCHEMBL2067538 | 0.70 | ALDH1A1 (0.68) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL5731180 | 0.67 | ALDH1A1 (0.58) | CA1CA2SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL22145982 | 0.67 | SLC40A1 (0.59) | CA1CA2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9577215 | 0.65 | CA12 (0.49) | CA1CA2LMNAALDH1A1MEN1 | |
| SCHEMBL16263833 | 0.65 | SLC40A1 (0.52) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4959500-A | Polybrominated bis sulfonamides | ETHYL CORPORATION (US) | 1990-09-25 | — | — | US | disclosed |