Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833698 | 0.88 | ALOX5 (0.62) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL2885897 | 0.88 | ALOX5 (0.62) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| Hydrochloric Acid SCHEMBL6948842 | 0.86 | ALOX5 (0.60) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL2170633 | 0.85 | ALOX5 (0.67) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6948837 | 0.85 | ALOX5 (0.59) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL6266373 | 0.84 | LTA4H (0.59) | ALOX5MAOBLMNAL3MBTL1ACACB | |
| SCHEMBL28353364 | 0.84 | MRGPRX4 (0.59) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL7401422 | 0.82 | LMNA (0.71) | ALOX5MAOBNR4A1NR4A2NR4A3 | |
| SCHEMBL13802503 | 0.81 | RXRA (0.57) | ALOX5RXRARXRBLMNAFFAR1 | |
| SCHEMBL27616913 | 0.81 | MAOB (0.56) | ALOX5MAOBNR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |