Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168406 | 0.82 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL8036416 | 0.81 | TAAR1 (0.42) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL608419 | 0.80 | PYCR1 (0.44) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL397145 | 0.80 | TAAR1 (0.56) | TDP1TP53ALDH1A1KDM4EMEN1 | |
| SCHEMBL3299248 | 0.79 | PYCR1 (0.47) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL6547406 | 0.79 | TAAR1 (0.48) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL18242698 | 0.78 | PYCR1 (0.40) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL5350848 | 0.77 | PYCR1 (0.46) | PYCR1TDP1TP53ALDH1A1KDM4E | |
| SCHEMBL11518880 | 0.76 | HDAC3 (0.42) | TP53SMN1; SMN2LMNACYP1A2 | |
| SCHEMBL17351794 | 0.76 | P2RX7 (0.39) | TAAR1HTTCYP1A2CYP2A6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | claimed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| CN-113387055-B | Film, method for producing film, and bag | 住友化学株式会社 | 2024-06-07 | — | — | CN | disclosed |
| CN-117425653-A | Method for producing bipyridine derivative, method for producing macrocyclic compound, method for producing metal complex containing macrocyclic compound as ligand, metal complex, electrode for air battery, and air battery | 住友化学株式会社 | 2024-01-19 | — | — | CN | disclosed |
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2024-01-18 | — | — | US | disclosed |
| US-20230165252-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-11643533-B2 | Film, method of producing film, and bag | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2023-05-09 | — | — | US | disclosed |
| CN-112638997-B | Film and packaging container | 住友化学株式会社 | 2023-04-28 | — | — | CN | disclosed |
| US-20230064576-A1 | HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-03-02 | — | — | US | disclosed |
| WO-2023013589-A1 | RADIOACTIVE METAL COMPLEX AND METHOD FOR PRODUCING SAME, AND RADIOACTIVE METAL SCAVENGER | 住友化学株式会社 | 2023-02-09 | — | — | WO | disclosed |
| WO-2022249992-A1 | PRODUCTION METHOD FOR BIPYRIDINE DERIVATIVE, PRODUCTION METHOD FOR MACROCYCLIC COMPOUND, PRODUCTION METHOD FOR METAL COMPLEX INCLUDING MACROCYCLIC COMPOUND AS LIGAND, METAL COMPLEX, ELECTRODE FOR AIR BATTERY, AND AIR BATTERY | 住友化学株式会社 | 2022-12-01 | — | — | WO | disclosed |
| US-4271295-A | HALOGENATION STEP | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4271296-A | CEPHALOSPORINS AND DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1981-06-02 | — | — | US | disclosed |
| US-4220766-A | FROM PENICILLINS | SHIONOGI & CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4220647-A | MUSCLE RELAXANTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4183855-A | INTERMEDIATES FOR PREPARATION OF THE BACTERICIDE, 1-OXADETHIA-CEPHALOSPORIN | SHIONOGI & CO., LTD. (JP) | 1980-01-15 | — | — | US | disclosed |
| US-4183928-A | Haloarylmalonamidooxacephalosporins | SHIONOGI AND CO., LTD. (JP) | 1980-01-15 | — | — | US | disclosed |
| US-4139530-A | CATIONIC DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-13 | — | — | US | disclosed |
| US-3978063-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-08-31 | — | — | US | disclosed |
| US-3963725-A | 1,2,3,4-Tetrahydroisoquinoline derivatives and the preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016152-A1 | ACTIVE COMPOUND COMBINATIONS | CYP51A1, ERG28, BROX | PYCR1 2108/4885TDP1 2571/4885TP53 4508/4885 |
| US-20230064576-A1 | HETEROCYCLYL PYRIDAZINE AS FUNGICIDAL COMPOUNDS | PNPO, PDXK, BLVRB | PYCR1 166/4885TDP1 1287/4885TP53 3322/4885 |
| US-20230165252-A1 | ACTIVE COMPOUND COMBINATIONS | CYP51A1, ERG28, BROX | PYCR1 2108/4885TDP1 2571/4885TP53 4508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.