Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2064312 | 0.98 | ACHE (0.54) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL31157559 | 0.98 | ACHE (0.54) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL17769110 | 0.84 | TAAR1 (0.59) | ACHETAAR1 | |
| SCHEMBL2386941 | 0.83 | ACHE (0.56) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL22566468 | 0.83 | ACHE (0.60) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL857370 | 0.82 | ACHE (0.54) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL10187102 | 0.81 | L3MBTL1 (0.60) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL14915784 | 0.80 | L3MBTL1 (0.45) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL8231646 | 0.79 | ACHE (0.56) | ACHEALDH1A1CYP3A4MAPTMAPK1 | |
| SCHEMBL11211872 | 0.79 | KDM4E (0.50) | ALDH1A1MAPTMAPK1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3235811-B1 | PROCESS OF PREPARING OXALAMIDES | SENOMYX INC (US) | 2018-07-25 | — | — | EP | claimed |
| CN-105152940-A | Comestible compositions comprising high potency savory flavorants, and processes for producing them | SENOMYX INC | 2015-12-16 | — | — | CN | claimed |
| CN-102311352-B | Synthesis method for 2-methoxy-4-methylbenzylamine | SHANGHAI INST TECHNOLOGY | 2013-10-16 | — | — | CN | claimed |
| US-8148536-B2 | Comestible compositions comprising high potency savory flavorants, and processes for producing them | SENOMYX, INC. (US) | 2012-04-03 | — | — | US | claimed |
| US-20090280230-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. | 2009-11-12 | — | — | US | claimed |
| EP-2010009-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | Senomyx, Inc. (US) | 2009-01-07 | — | — | EP | claimed |
| WO-2007124152-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. (US) | 2007-11-01 | — | — | WO | claimed |
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | WESTERN UNIVERSITY OF HEALTH SCIENCES (US) | 2026-04-21 | — | — | US | disclosed |
| EP-3398452-B1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS | FIRMENICH INCORPORATED (US) | 2024-10-02 | — | — | EP | disclosed |
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | NOVARTIS AG (CH) | 2023-10-17 | — | — | US | disclosed |
| US-20230128006-A1 | SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME | APTINYX INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230091121-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | UNITED STATES GOVERNMENT | 2023-03-23 | — | — | US | disclosed |
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2022-10-13 | — | — | US | disclosed |
| WO-2007124152-A2 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | SENOMYX, INC. (US) | 2007-11-01 | — | — | WO | disclosed |
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| EP-1659881-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| WO-2005041684-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX INC. (US) | 2005-05-12 | — | — | WO | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787785-B2 | Pyrazolopyridine derivatives and uses thereof | HBZ, ZFX, WIZ | ACHE 4474/4885ALDH1A1 1243/4885CYP3A4 2883/4885 |
| US-20230091121-A1 | CALPAIN-2 INHIBITOR COMPOUNDS AND METHODS OF TREATMENT | CAPN2, CAPNS1, CAPN1 | ACHE 916/4885ALDH1A1 3467/4885CYP3A4 4608/4885 |
| US-12606520-B2 | Calpain-2 inhibitor compounds and methods of treatment | CAPN2, CAPN1, CAPNS1 | ACHE 795/4885ALDH1A1 3630/4885CYP3A4 4357/4885 |
| US-20230128006-A1 | SPIRO-LACTAM NMDA MODULATORS AND METHODS OF USING SAME | GRIN1, GRIN2A, GRIN2C | ACHE 208/4885ALDH1A1 2935/4885CYP3A4 3031/4885 |
| US-20090280230-A1 | COMESTIBLE COMPOSITIONS COMPRISING HIGH POTENCY SAVORY FLAVORANTS, AND PROCESSES FOR PRODUCING THEM | TAS1R1, TAS1R2, GRM1 | ACHE 1571/4885ALDH1A1 698/4885CYP3A4 4326/4885 |
| US-20220326230-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | ACHE 722/4885ALDH1A1 1089/4885CYP3A4 3465/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | ACHE 719/4885ALDH1A1 1936/4885CYP3A4 2119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.