Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9704051 | 0.80 | RAB9A (0.44) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9704045 | 0.80 | RAB9A (0.44) | RAB9AALDH1A1NPC1MEN1KMT2A | |
| SCHEMBL9588271 | 0.79 | DRD2 (0.34) | ALDH1A1MEN1KMT2AMAPTPDK2 | |
| SCHEMBL9589012 | 0.79 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2APOLBCYP1A2 | |
| SCHEMBL9588012 | 0.79 | IDO1 (0.34) | MAPTPDK2 | |
| SCHEMBL9587643 | 0.78 | ALDH1A1 (0.32) | RAB9AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9702059 | 0.78 | ALDH1A1 (0.32) | RAB9AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL9587842 | 0.77 | MEN1 (0.41) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9701823 | 0.77 | MEN1 (0.41) | RAB9AALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9588559 | 0.76 | HSD17B1 (0.34) | MEN1KMT2AMAPTCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208246-A | Hypotensive, bronchodilator | J. URIACH & CIA. (ES) | 1993-05-04 | — | — | US | claimed |
| EP-0489300-A2 | Tetralones with pharmacological activity | J. URIACH & CIA. S.A. (ES) | 1992-06-10 | — | — | EP | claimed |
| US-5272170-A | Tetralones with pharmacological activity | J. URIACH & CIA., S.A. (ES) | 1993-12-21 | — | — | US | disclosed |
| US-5208246-A | Hypotensive, bronchodilator | J. URIACH & CIA. (ES) | 1993-05-04 | — | — | US | disclosed |