Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2033213 | 0.80 | MT-CO2 (0.69) | MT-CO2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL28581289 | 0.76 | ADRA2A (0.49) | KMT2ATDP2NSD2ADRA2AADRA2B | |
| SCHEMBL3220136 | 0.72 | PDE4B (0.45) | MT-CO2KMT2AMEN1NSD2ALDH1A1 | |
| SCHEMBL29793056 | 0.71 | KIF11 (0.60) | KMT2ATDP2NSD2ADRA2AADRA2B | |
| SCHEMBL1368828 | 0.71 | KIF11 (0.60) | KMT2ATDP2NSD2ADRA2AADRA2B | |
| SCHEMBL9275585 | 0.70 | MT-CO2 (0.70) | MT-CO2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL9686975 | 0.70 | MT-CO2 (0.41) | MT-CO2KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL3988142 | 0.70 | KMT2A (0.65) | MT-CO2KMT2AMEN1POLBRAB9A | |
| SCHEMBL678399 | 0.69 | CYP11B2 (0.51) | ALDH1A1 | |
| SCHEMBL15102230 | 0.69 | IDH2 (0.50) | MT-CO2KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5331144-A | — | — | None | — | — | JP | disclosed |
| JP-H05331144-A | CYCLOHEXENONE COMPOUND AND CEREBRAL FUNCTION IMPROVER COMPRISING THE SAME AS ACTIVE INGREDIENT | NIKKEN CHEM CO LTD | 1993-12-14 | — | — | JP | disclosed |