Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865971 | 0.81 | MCHR1 (0.35) | MCHR1TOP1 | |
| SCHEMBL10559619 | 0.81 | GABRP (0.39) | — | |
| SCHEMBL9602906 | 0.80 | MCHR1 (0.35) | MCHR1TOP1 | |
| SCHEMBL9602580 | 0.78 | MCHR1 (0.39) | MCHR1TOP1 | |
| SCHEMBL9865071 | 0.77 | MCHR1 (0.38) | MCHR1TOP1 | |
| SCHEMBL9865444 | 0.77 | MCHR1 (0.38) | MCHR1TOP1 | |
| SCHEMBL9603147 | 0.75 | MCHR1 (0.35) | MCHR1TOP1 | |
| SCHEMBL9602794 | 0.74 | CHRM2 (0.32) | — | |
| SCHEMBL7288041 | 0.72 | MAPT (0.34) | — | |
| SCHEMBL9602271 | 0.72 | MCHR1 (0.39) | MCHR1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351435-B1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5045541-A | Immunodeficiency disorders | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0351435-A1 | FUSED PYRIDAZINE COMPOUNDS AND THEIR MEDICINAL USES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1990-01-24 | — | — | EP | disclosed |